May 1, 2005Echocardiography
Stunning of the Left Atrium after Conversion of Atrial Fibrillation: Predictor for Maintenance of Sinus Rhythm?
Key result
Mitral inflow A-wave velocity 24 hours after cardioversion positively correlated with the maintenance of sinus rhythm (r=0.96, P=0.008).
Why the study?
Does mitral inflow A-wave velocity measured 24 hours after cardioversion predict recurrence of atrial fibrillation in patients with nonvalvular atrial fibrillation?
Population
187 consecutive patients with nonvalvular atrial fibrillation who had been cardioverted to sinus rhythm from…
Design
Cohort
Follow-up
>365 days
Authors
Discussion
Loading...
Member takes
Implication
May aid post-cardioversion AF recurrence prediction; hypothesis-generating and requires prospective validation.
Key Points
- To evaluate the effectiveness of mitral inflow A-wave velocity in predicting atrial fibrillation recurrence after cardioversion.
- 187 patients with nonvalvular atrial fibrillation were studied following cardioversion.
- Transthoracic echocardiography measured left atrial diameter, left ventricular ejection fraction, and mitral inflow A-wave velocity 24 hours post-cardioversion.
- Patients were categorized based on recurrence time into five different groups.
- Maintenance of sinus rhythm is negatively correlated with age (-0.97, P=0.006), left atrial diameter (-0.93, P=0.02), and atrial fibrillation duration (-0.93, P=0.02).
- Mitral inflow A-wave velocity shows a positive correlation with maintenance of sinus rhythm (0.96, P=0.008).
- Higher recurrence frequency occurs in patients with slow mitral inflow A-wave velocity after pharmacological cardioversion (0.89, P=0.004).
Study Design
Type
Cohort (n=187)
Structured PICO
Does mitral inflow A-wave velocity measured 24 hours after cardioversion predict recurrence of atrial fibrillation in patients with nonvalvular atrial fibrillation?
P
Population
187 consecutive patients with nonvalvular atrial fibrillation who had been cardioverted to sinus rhythm, evaluated for recurrence over >365 days.
E
Exposure
Measurement of mitral inflow A-wave velocity by transthoracic echocardiography 24 hours after cardioversion
O
Outcome
Recurrence of atrial fibrillation (evaluated at <30 days, 31-90 days, 91-180 days, 181-365 days, and >365 days)
Main Result
Effect estimate: r = 0.96
p-value: p=0.008
Mitral inflow A-wave velocity measured 24 hours after cardioversion, along with age, AF duration, and LA diameter, can help predict the maintenance of sinus rhythm, especially in patients undergoing pharmacological cardioversion.
Cite This Study
Ökçün et al. (2005) conducted a cohort in Nonvalvular atrial fibrillation (n=187). Mitral inflow A-wave velocity was evaluated on Maintenance of sinus rhythm (r = 0.96, p=0.008). Mitral inflow A-wave velocity 24 hours after cardioversion positively correlated with the maintenance of sinus rhythm (r=0.96, P=0.008).