Key result
The overall rate of medication adherence among hypertensive patients was 42.4%, with urban residents having significantly higher odds of good adherence compared to rural residents (OR 3.65).
Why the study?
This study aimed to assess the level of medication adherence and its associated factors among hypertensive patients.
Cross-Sectional (n=2,835)
Yes
Odds Ratio: 3.65 (95% CI 3.01–4.43)
Absolute Event Rate: 68.2% vs 22.3%
p-value: p=<0.001
Medication adherence among hypertensive patients in Northeast China is low (42.4%), and better adherence is associated with older age, urban residence, longer disease duration, and better knowledge, attitude, and practice, leading to improved blood pressure control.
Low adherence signals need for rural-focused strategies; leaves open whether interventions targeting disparities improve outcomes.
This study aimed to assess the level of medication adherence and its associated factors among hypertensive patients. From 26 May 2019 to 24 March 2021, a multistage stratified cluster random sampling method was used to randomly select 8 communities and 7 villages from 7 cities in Northeast China. A questionnaire survey was performed on 2,835 eligible hypertensive patients aged ≥ 40 years. The 4-Item Morisky Medication Adherence Scale was used to evaluate the level of medication adherence. The overall rate of medication adherence in hypertensive patients was 42.4%, male and female were 44.3% and 41.2% respectively. The rate in urban was higher in rural (68.2% vs 22.3%, P < 0.001). Multivariate Logistic regression analysis showed that patients with age 70 and above (OR: 1.78), urban (OR: 3.65), family history of hypertension (OR: 1.26), over 15 years duration of hypertension (OR: 1.36), good knowledge (OR: 1.67), good attitude (OR: 2.08) and good practice (OR: 2.12) had good adherence in hypertensive patients. The mean SBP and DBP of hypertensive patients with good adherence were lower than poor adherence (151.4 mmHg vs 154.8 mmHg, P < 0.001; 89.0 mmHg vs 90.5 mmHg, P = 0.001). The rate of BP control was 20.6%, patients with good adherence was higher than those of patients with poor adherence (23.8% vs 18.3%, P < 0.001). The level of medication adherence is lower among hypertensive patients in Northeast China. It is urgent to strengthen the management of medication adherence and improve the control in hypertensive patients.
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Wang et al. (2022) conducted a cross-sectional in Hypertension (n=2,835). Urban residence vs. Rural residence was evaluated on Good medication adherence (OR 3.65, 95% CI 3.01-4.43, p=<0.001). The overall rate of medication adherence among hypertensive patients was 42.4%, with urban residents having significantly higher odds of good adherence compared to rural residents (OR 3.65).
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