What question did this study set out to answer?

To evaluate the association between antihypertensive medication adherence and blood pressure control, and to identify risk factors influencing adherence in hypertensive patients.

October 16, 2014Journal of Evaluation in Clinical Practice

Effect of medication adherence on blood pressure control and risk factors for antihypertensive medication adherence

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Why the study?

Does medication adherence improve blood pressure control in Chinese hypertensive patients?

Population

232 Chinese hypertensive patients in a comprehensive teaching hospital in Shanghai, China

Design

Cross-sectional

Authors

ZYZhao YueFudan University BWBin WangJinzhong University WQWeilin QiSir Run Run Shaw Hospital

Discussion

Member takes

Implication

Supports adherence strategies for systolic control; extends observational data but leaves causality and generalizability open.

Key Points

To evaluate the association between antihypertensive medication adherence and blood pressure control, and to identify risk factors influencing adherence in hypertensive patients.
Cross-sectional study conducted among hypertensive patients at a comprehensive teaching hospital in Shanghai, China (N=232).
Data collected via a validated adherence scale, a self-designed questionnaire, and patient medical records.
High, medium, and low adherence were reported in 51.7% (n=120), 22.0% (n=51), and 26.3% (n=61) of participants, respectively.
Adjusted analysis showed medication adherence was significantly associated with systolic blood pressure control (P=0.001), but not diastolic control (P=0.334).
Multivariate analysis identified higher adherence with longer drug use duration (OR=0.46, 95% CI 0.25–0.84, P=0.012), antiplatelet therapy (OR=0.38, 95% CI 0.20–0.71, P=0.002), fewer cost concerns (OR=0.18, 95% CI 0.02–0.51, P=0.001), professional guidance (OR=0.34, 95% CI 0.17–0.66, P=0.002), and family support (OR=0.51, 95% CI 0.27–0.96, P=0.036).

Structured PICO

Does medication adherence improve blood pressure control in Chinese hypertensive patients?

Population

232 Chinese hypertensive patients in a comprehensive teaching hospital in Shanghai, China

Intervention

Antihypertensive medication adherence

Outcome

Blood pressure control (systolic and diastolic) and risk factors for adherencesurrogate

Suboptimal medication adherence is common among Chinese hypertensive patients and is significantly associated with poorer systolic blood pressure control.

Cite This Study

Yue et al. (2014) studied this question.

synapsesocial.com/papers/6a8157760914b5fb8de3fa6a https://doi.org/10.1111/jep.12268

Topics

Hypertension management

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Effect of medication adherence on blood pressure control and risk factors for antihypertensive medication adherence

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Effect of medication adherence on blood pressure control and risk factors for antihypertensive medication adherence

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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