Why the study?
Physical activity intensity remains a key determinant in managing chronic conditions, but how the proportion of moderate-to-vigorous physical activity relative to total volume independently relates to cognitive function and depressive symptoms in middle-aged and older adults was unclear.
Is the proportion of moderate-to-vigorous physical activity associated with cognitive function and depressive symptoms in middle-aged and older adults?
Population
17,057 middle-aged and older adults in the China Health and Retirement Longitudinal Study
Comparison
Different proportions of MVPA relative to total physical activity volume
Design
Cross-sectional analysis
Key result
A 1%-33% proportion of moderate-to-vigorous physical activity was associated with the lowest odds of cognitive impairment (aOR 0.48; 95% CI 0.35-0.67) and depressive symptoms in older adults.
Authors
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May support moderate MVPA proportions for cognitive and mental health in older adults; leaves open causality and need for prospective confirmation.
Cross-Sectional (n=17,057)
Yes
Is the proportion of moderate-to-vigorous physical activity associated with cognitive function and depressive symptoms in middle-aged and older adults?
Odds Ratio: 0.48 (95% CI 0.35–0.67)
A proportion of 1%-33% moderate-to-vigorous physical activity relative to total physical activity volume is associated with the lowest odds of cognitive impairment and depressive symptoms in older adults.
Ge et al. (2026) reported a cross-sectional. 1%-33% moderate-to-vigorous physical activity (MVPA) proportion vs. Other proportions of MVPA was evaluated on Cognitive impairment (aOR 0.48, 95% CI 0.35-0.67). A 1%-33% proportion of moderate-to-vigorous physical activity was associated with the lowest odds of cognitive impairment (aOR 0.48; 95% CI 0.35-0.67) and depressive symptoms in older adults.
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