Key result
Left anterolateral thoracotomy and median sternotomy for pericardiectomy yielded similar mortality (14.2% vs 13.3%) and comparable improvements in NYHA status.
Why the study?
Does median sternotomy compared to left anterolateral thoracotomy improve outcomes in patients undergoing pericardiectomy for constrictive pericarditis?
Cohort (n=36)
Does median sternotomy compared to left anterolateral thoracotomy improve outcomes in patients undergoing pericardiectomy for constrictive pericarditis?
Absolute Event Rate: 14.2% vs 13.3%
Both median sternotomy and left anterolateral thoracotomy are effective approaches for pericardiectomy in constrictive pericarditis, yielding similar mortality and symptomatic improvement.
Either approach yields similar mortality and NYHA gains; leaves open need for randomized trials to guide selection.
Pericardiectomy is the definitive treatment for constrictive pericarditis but the best surgical approach remains controversial. In this study we compared the results of pericardiectomy performed on 36 patients with constrictive pericarditis between 1995 and 2001. Pericardiectomy was performed by median sternotomy in 15 patients and by left anterolateral thoracotomy in 21 patients. All patients were reviewed at 6 weeks post operatively. Both groups of patients were similar in age, sex distribution, NYHA shortness of breath status, aetiology, presenting symptoms and duration of symptoms. Mortality was similar in the two groups with three deaths (14.2%) in the thoracotomy group and two deaths (13.3%) in the median sternotomy group. NYHA status improved in both thoracotomy (3.0+/-0.8 to 1.6+/-0.7; P=3.3x10(-6)) and median sternotomy (2.9+/-0.7 to 1.5+/-0.6; P=2.8x10(-5)) groups. The degree of improvement was not significant between the two groups (P=0.63). In addition ionotropic support and postoperative hospital stay were similar between the two groups. There was a higher incidence of wound infections (23.8 versus 6.6%; P=0.13) and pulmonary complications (23.8 versus 13.3%; P=0.33) associated with thoracotomy. In conclusion pericardiectomy improves NYHA status in all patients and mortality rates are similar in both the approaches.
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Tiruvoipati et al. (2003) conducted a cohort in Constrictive pericarditis (n=36). Left anterolateral thoracotomy vs. Median sternotomy was evaluated on Mortality. Left anterolateral thoracotomy and median sternotomy for pericardiectomy yielded similar mortality (14.2% vs 13.3%) and comparable improvements in NYHA status.
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