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June 10, 2026CureusOpen Access

Incidental Diagnosis of a Well-Differentiated Appendiceal Neuroendocrine Tumor Following Appendectomy for Complicated Acute Appendicitis: A Case Report

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Authors

BBBrayan BenguecheaMexican Social Security InstituteOCOscar A CastroMexican Social Security InstituteACAndrea N Garza CisnerosInstitute for Social Security and Services for State Workers

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Overview

Case report shows a well-differentiated appendiceal neuroendocrine tumor in a 72-year-old after surgery, suggesting the need for histopathological review.

Key Points

  • The aim is to highlight the incidental diagnosis of appendiceal neuroendocrine tumors during appendectomy for acute appendicitis.
  • Urgent open appendectomy performed on a 72-year-old woman with suspected acute appendicitis.
  • Histopathological examination evaluated the appendectomy specimen for tumors.
  • Postoperative clinical follow-up conducted without additional surgical intervention.
  • Histopathological findings confirmed a well-differentiated appendiceal neuroendocrine tumor (NET G1, WHO grade 1) with negative surgical margins.
  • No lymphovascular invasion was detected, and the mitotic index was less than 1/mm².
  • The patient's postoperative recovery was uneventful, leading to discharge on postoperative day three.

Cite This Study

Benguechea et al. (2026) studied this question.

synapsesocial.com/papers/6a28fe716f82f25be989badfhttps://doi.org/10.7759/cureus.110421
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Appendiceal Neuroendocrine Tumor Presenting as Acute Appendicitis: A Case Report2026
  2. 2A case of appendiceal neuroendocrine tumor with metastatic spread in a young patient2025
  3. 3Benign or by Chance: A Case Report on Incidental Appendectomy Revealing a Neuroendocrine Tumor During Traumatic Exploratory Laparotomy2024 · 1 citations
  4. 4Clinical Approach to Incidentally Identified Appendiceal Neuroendocrine Neoplasms After Appendicectomy in Children2025
  5. 5Incidental appendiceal neoplasms: Single-centre results2023 · 3 citations