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October 1, 2023Indian Journal of CancerOpen Access

Incidental appendiceal neoplasms: Single-centre results

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Authors

HÖHakan ÖzdemirZÖZehra Ünal ÖzdemirMGMehmet Onur Gül

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Overview

Retrospective study reveals incidental malignancies in 1.4% of appendectomy specimens, indicating appendectomy alone suffices for most neuroendocrine and mucinous tumors.

Key Points

  • To identify and characterize incidental appendiceal malignancies in patients undergoing surgery for suspected acute appendicitis.
  • Retrospective review of patients undergoing appendectomy with a pre-diagnosis of acute appendicitis between January 2013 and December 2018 (N=2336).
  • Evaluated histopathological parameters including tumor type, size, grade, surgical margins, Ki-67 index, lymphovascular/perineural invasion, and postoperative follow-up.
  • Malignant or premalignant lesions were identified in 32 of 2336 specimens (1.4%): 16 neuroendocrine tumors (0.7%), 11 low-grade appendiceal mucinous neoplasms (0.5%), and 5 primary appendiceal carcinomas (0.2%).
  • Appendectomy provided sufficient treatment for the majority of neuroendocrine and mucinous tumors, whereas adenocarcinoma cases required subsequent right hemicolectomy.

Cite This Study

Özdemir et al. (2023) studied this question.

synapsesocial.com/papers/6a87a64c5bd561ae69aca0f9https://doi.org/10.4103/ijc.ijc_450_20
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence of malignancy in appendiceal surgical specimens: A retrospective single-center study2026
  2. 2Retrospective analysis of the incidence of appendiceal neoplasm and malignancy in patients treated for suspected acute appendicitis2024 · 10 citations
  3. 3Survival among 148 patients with an incidentally detected appendiceal tumours at surgery for acute appendicitis: a population-based cohort follow-up study2024 · 3 citations
  4. 4Clinicopathological Profile and Management of Appendiceal Neoplasm: An Observational Study2025
  5. 5Incidental Diagnosis of a Well-Differentiated Appendiceal Neuroendocrine Tumor Following Appendectomy for Complicated Acute Appendicitis: A Case Report2026