Key result
Complete surgical excision plus postoperative cyclophosphamide yields no tumor recurrence in a pediatric case.
Why the study?
Myxoid liposarcoma predominantly affects adolescents and young adults, making its occurrence exceptionally rare in children under five years of age.
Case Report (n=1)
Complete surgical excision followed by cyclophosphamide chemotherapy can lead to a favorable outcome in exceptionally rare cases of early childhood retroperitoneal myxoid liposarcoma.
Rare pediatric myxoid liposarcoma case supports inclusion in abdominal mass differentials; leaves open standardized protocols and long-term outcomes.
Myxoid liposarcoma is a malignant soft tissue sarcoma of adipocytic origin that predominantly affects adolescents and young adults. It is exceptionally rare in early childhood, with very few reported cases in children under the age of five. We present a rare case of a 3.5-year-old male child who was admitted to our emergency unit with a large abdominal mass. The patient underwent an exploratory laparotomy with complete excision of the mass, achieving negative surgical margins. Histopathological analysis confirmed the diagnosis of well-differentiated myxoid liposarcoma. The patient subsequently received six cycles of postoperative cyclophosphamide chemotherapy, administered at 20-day intervals. Follow-up tomography scan confirmed a favorable outcome with no evidence of recurrence.
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Hakimi et al. (2026) conducted a case report in Retroperitoneal myxoid liposarcoma (n=1). Exploratory laparotomy with complete excision and postoperative cyclophosphamide was evaluated on Recurrence. Complete surgical excision followed by six cycles of postoperative cyclophosphamide chemotherapy resulted in a favorable outcome with no evidence of recurrence in a 3.5-year-old child.
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