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This review aims to discuss the pathophysiology, diagnosis, and treatment of disseminated intravascular coagulation (DIC).

June 10, 2026Open Access

Disseminated Intravascular Coagulation Syndrome: The Modern Paradigm of Pathophysiology, Early Diagnosis, and Personalized Therapy

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Review reveals classification and early diagnosis strategies for DIC, suggesting improved management in affected individuals.

This review aims to discuss the pathophysiology, diagnosis, and treatment of disseminated intravascular coagulation (DIC).
Reviewed 50 scientific publications from the last five years on DIC syndromes related to surgical procedures, trauma, and sepsis.
Analyzed existing strategies for early diagnosis and personalized management approaches.
DIC is characterized by systemic activation of coagulation and impaired fibrinolysis.
Mortality rate remains high, up to 78% in critical conditions.
New 2025 phase classification offers improved understanding for tailored therapeutic strategies.

Zaynutdinova et al. (2026) studied this question.

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