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June 10, 2026Open Access

Disseminated Intravascular Coagulation Syndrome: The Modern Paradigm of Pathophysiology, Early Diagnosis, and Personalized Therapy

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Authors

DZD.L. ZaynutdinovaTashkent Pediatric Medical InstituteMBM.U. BerdiyorovaTashkent Pediatric Medical Institute

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Implication

Review explores pathophysiology and early diagnosis of DIC syndrome, highlighting personalized treatment strategies.

Key Points

  • This article aims to review the pathophysiology, early diagnosis, and treatment options for disseminated intravascular coagulation syndrome.
  • Analysis of 50 scientific publications from the last five years related to DIC syndrome.
  • Focus on surgical procedures, trauma, and sepsis as contributing factors.
  • Evaluation of new classifications and early diagnostic strategies.
  • Mortality associated with DIC can reach up to 78% in critical conditions.
  • New 2025 phase classification provides updated insights into patient management.
  • Personalized therapy approaches show promise for improving outcomes in DIC.

Cite This Study

Zaynutdinova et al. (2026) studied this question.

synapsesocial.com/papers/6a2901e26f82f25be989de27https://doi.org/10.5281/zenodo.20590369
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1DISSEMINATED INTRAVASCULAR COAGULATION SYNDROME: THE MODERN PARADIGM OF PATHOPHYSIOLOGY, EARLY DIAGNOSIS, AND PERSONALIZED THERAPY2026
  2. 2Disseminated intravascular coagulation2014 · 55 citations
  3. 3Disseminated Intravascular Coagulation1999 · 120 citations
  4. 4Revisiting the Concept of DIC: A Phenotype-guided Framework for Modern Hemostatic Medicine2026
  5. 5Traumatic disseminated intravascular coagulation: a narrative review of modern concepts in pathophysiology, diagnosis, and management2026