Randomized trial demonstrates naltrexone’s effectiveness for managing obsessive sexual symptoms in individuals with neurodevelopmental disorders, suggesting new treatment avenues.
Key Points
To evaluate the effectiveness of naltrexone for managing compulsive sexual behavior and related symptoms in a patient with neurodevelopmental comorbidities.
Descriptive case report of a man in his 20s with multiple psychiatric diagnoses and severe intrusive sexual thoughts.
Patient was hospitalized due to acute distress and safety concerns related to symptoms.
Naltrexone administration initiated after multiple psychotropic optimizations, with symptom tracking over 16 days.
Marked improvement in symptoms observed within 5 days after initiating naltrexone.
Complete resolution of intrusive sexual thoughts by hospital day 16.
The rapid response indicates potential for naltrexone as an intervention for severe and ambiguous sexual compulsive symptoms.