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June 12, 2026Ear and Hearing

Cochlear Nerve Responsiveness to Electrical Stimulation in Late-Implanted Prelingually Deafened Adults

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Authors

XCXiuhua ChaoXLXianqi LiuJLJianfen Luo

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Overview

Randomized trial evaluates cochlear nerve response to stimulation in prelingually and postlingually deafened adults, highlighting neural recruitment differences.

Key Points

  • This study aims to evaluate the cochlear nerve responsiveness to electrical stimulation in prelingually deafened adults and compare it with postlingually deafened adults.
  • Participants included 15 prelingually and 11 postlingually deafened adults using Cochlear Nucleus implants.
  • eCAPs were recorded at different electrode locations and under various inter-phase gap conditions.
  • A linear mixed-effects model analyzed the effects of groups, electrode locations, and IPGs on dependent variables.
  • Prelingually deafened adults had significantly shallower eCAP input/output function slopes compared to postlingually deafened adults.
  • The postlingual group showed significantly larger IPG-induced increases in maximum amplitude than the prelingual group.
  • Electrode-specific analyses revealed reduced eCAP amplitudes at basal electrodes in the postlingual group, not seen in the prelingual group.

Cite This Study

Chao et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba3fa8101cf8926f027bbhttps://doi.org/10.1097/aud.0000000000001850
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  1. 1An Electrically Evoked Compound Action Potential Marker for Local Spiral Ganglion Neuron Degeneration: The Failure Index2024 · 8 citations
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  3. 3Neural recovery function of the auditory nerve in cochlear implant surgery: Comparison between different regions of the cochlea2022 · 3 citations
  4. 4Responsiveness of the Electrically Stimulated Cochlear Nerve in Children With Cochlear Nerve Deficiency2017 · 86 citations