Stress independently predicted disease burden in patients with cardiometabolic syndrome (β=0.373, p=0.003), whereas depression, anxiety, and vital exhaustion did not.
Cross-Sectional (n=143)
Do psychological dimensions such as stress, anxiety, and depression correlate with disease burden in patients with cardiometabolic syndrome?
Stress is an independent predictor of disease burden in patients with cardiometabolic syndrome, highlighting the potential value of stress management interventions in preventive cardiology.
Effect estimate: β=0.373
p-value: p=0.003
Abstract Background/Introduction Cardiometabolic syndrome (CMS) is a cluster of conditions increasing cardiovascular risk, often accompanied by significant disease burden. Psychological factors such as depression, anxiety, and stress may exacerbate this burden, yet their associations in Eastern European populations remain underexplored. Purpose This study aimed to identify psychological dimensions correlating with disease burden in individuals with CMS in an Eastern European country. Methods A cross-sectional study recruited 143 participants (58 men, 84 women; mean age 51.7 years, SD=16.8) diagnosed with CMS. Validated questionnaires assessed depression (Depression, Anxiety and Stress Scale (DASS-21), anxiety (DASS-21), stress (DASS-21), vital exhaustion (Vital Exhaustion Questionnaire), social support (MOS Social Support Survey), and health locus of control (Multidimensional Health Locus of Control Scale). Disease burden was measured using the Disease Burden Scale. Pearson correlations examined bivariate associations, and multiple linear regression modelled predictors of disease burden, adjusting for all psychological variables. Results Disease burden positively correlated with depression (r=0.339, p0.001), anxiety (r=0.357, p0.001), stress (r=0.454, p0.001), vital exhaustion (r=0.402, p0.001), and external random health control (r=0.171, p0.05), and negatively with social support (r=-0.163, p=0.005). The regression model explained 25.6% of variance (adjusted R²=0.223; F(6,135)=7.744, p0.001). Stress was the only significant predictor (β=0.373, p=0.003), with non-significant effects for depression (β=-0.150, p=0.234), anxiety (β=0.078, p=0.459), vital exhaustion (β=0.171, p=0.109), social support (β=-0.130, p=0.095), and external random health control (β=0.116, p=0.156). Conclusion(s) Psychological distress, particularly stress, independently contributes to disease burden in CMS, highlighting the need for targeted stress management interventions in preventive cardiology to mitigate overall burden and improve outcomes.
Szucs et al. (Mon,) conducted a cross-sectional in Cardiometabolic syndrome (n=143). Psychological distress (stress, depression, anxiety) was evaluated on Disease burden (β=0.373, p=0.003). Stress independently predicted disease burden in patients with cardiometabolic syndrome (β=0.373, p=0.003), whereas depression, anxiety, and vital exhaustion did not.
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