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Efficacy of erector spinae plane block with liposomal bupivacaine for postoperative analgesia in patients undergoing open spinal surgery: a randomized controlled trial

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This study aims to evaluate the efficacy of erector spinae plane block with liposomal bupivacaine for postoperative analgesia in spinal surgery patients.
Randomly assigned 64 patients undergoing elective spinal surgery to receive either liposomal bupivacaine or ropivacaine for analgesia.
Measured primary outcome as incidence of rescue analgesia on the first postoperative day.
Evaluated secondary outcomes including VAS scores, opioid consumption, and patient satisfaction.
RB group had significantly higher incidence of rescue analgesic use on postoperative days 1, 2, and 3 (p < 0.05).
VAS scores were consistently higher in the RH group at 6, 12, 24, and 48 hours postoperatively.
ESPB with LB showed reduced opioid consumption and improved quality of recovery compared to RH group.

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Randomized trial evaluates analgesic efficacy of erector spinae plane block in spinal surgery, indicating benefits of liposomal bupivacaine.

Wang et al. (2026) studied this question.

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Randomized trial evaluates analgesic efficacy of erector spinae plane block in spinal surgery, indicating benefits of liposomal bupivacaine.