Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 13, 2026Frontiers in NeurologyOpen Access

Menopause and ageing in women with multiple sclerosis

View Full Paper
Ask AI
Bookmark
Share

Authors

CSCecilia Smith SimonsenECElisabeth Gulowsen Celius

Discussion

Loading...

Member takes

Overview

Narrative review explores menopause influence on disease activity and symptom burden in women with MS, suggesting complex interactions.

Key Points

  • This review investigates the relationship between menopause, biological ageing, and multiple sclerosis outcomes.
  • Narrative review based on structured literature search of PubMed
  • Supplemental reference screening for relevant studies
  • Current evidence does not support menopause as a distinct factor in relapse activity or MRI-defined inflammation.
  • Larger studies show no significant effect of menopause on EDSS progression when age is accounted for.
  • Symptom burden increases during midlife, influenced by hormonal changes and comorbidities.

Cite This Study

Simonsen et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf2a9faef96ed7f0556efhttps://doi.org/10.3389/fneur.2026.1838550
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Menopause Impact on Multiple Sclerosis Disability Progression2025
  2. 2The Neurology of Menopause2026
  3. 3Aging as a modulator of multiple sclerosis pathophysiology2026
  4. 4Expert Opinion on Age-Related Sex Hormone Changes and Hypogonadism in People With Multiple Sclerosis2026
  5. 5Biological markers of aging across the menopause transition: current evidence2026 · 1 citations