Demographics and Clinical Factors Associated with Persistence on Cannabidiol in US Patients with Lennox-Gastaut Syndrome (LGS), Dravet Syndrome (DS), Tuberous Sclerosis Complex (TSC), or Other Refractory Epilepsies (P10-10.004)

Leah Burn; Vicki Osborne; Arthur Sillah; Timothy Saurer; Michael Faithe; Maggie McCarter; Sanket Shah; Timothy Barnes; Arunima Sachdev; A Gupta; Mohankumar Kurukumbi

doi:10.1212/wnl.0000000000215667

June 9, 2026Neurology

Demographics and Clinical Factors Associated with Persistence on Cannabidiol in US Patients with Lennox-Gastaut Syndrome (LGS), Dravet Syndrome (DS), Tuberous Sclerosis Complex (TSC), or Other Refractory Epilepsies (P10-10.004)

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Key Points

This research aims to evaluate sociodemographic and clinical factors related to the persistence of cannabidiol treatment in patients with specific refractory epilepsies.
Evaluated patients with Lennox-Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex, or other refractory epilepsies.
Analyzed sociodemographic and clinical data associated with cannabidiol (Epidiolex) persistence.
Identified key sociodemographic factors linked to treatment persistence.
Examined clinical factors affecting cannabidiol adherence among various epilepsy types.

Implication

Evaluation identifies sociodemographic and clinical factors influencing cannabidiol use in refractory epilepsies, suggesting important treatment insights.

Abstract

To evaluate sociodemographic and clinical factors associated with persistence on plant-derived, highly purified CBD (Epidiolex® 100 mg/mL oral solution) among patients with LGS, DS, TSC, or other refractory epilepsies.

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Cite This Study

Burn et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf34dfaef96ed7f055be3 https://doi.org/10.1212/wnl.0000000000215667

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Demographics and Clinical Factors Associated with Persistence on Cannabidiol in US Patients with Lennox-Gastaut Syndrome (LGS), Dravet Syndrome (DS), Tuberous Sclerosis Complex (TSC), or Other Refractory Epilepsies (P10-10.004)

Key Points

Implication

Abstract

Discussion

Cite This Study

Demographics and Clinical Factors Associated with Persistence on Cannabidiol in US Patients with Lennox-Gastaut Syndrome (LGS), Dravet Syndrome (DS), Tuberous Sclerosis Complex (TSC), or Other Refractory Epilepsies (P10-10.004)

Key Points

Implication

Abstract

Discussion

Cite This Study

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