Effects of italicSaobai Huifeng Pill/italic (扫白茴风丸) on hemorheology in model guinea pigs with vitiligo

Key Points

• This research investigates the effects of Saobai Huifeng Pill on blood rheology and skin repigmentation in a vitiligo guinea pig model induced by hydrogen peroxide.
• 40 guinea pigs were randomly assigned to four groups: control, model, Saobai Huifeng Pill, and vitiligo pill.
• The model was created using 5% hydrogen peroxide and treatment was administered via percutaneous administration.
• Blood rheology parameters and pigmentation restoration were analyzed statistically after interventions.
• The plasma viscosity in the Saobai Huifeng Pill group was lower than in the vitiligo pill group (P<0.05).
• Whole blood viscosity at various shear rates was significantly improved in the Saobai Huifeng Pill group (P<0.01).
• Pigmentation restoration in the Saobai Huifeng Pill group showed better outcomes compared to the model group (P<0.01).