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June 13, 2026Pediatric DrugsOpen Access

Risks of Undertreatment and Overtreatment in Pediatric Inflammatory Bowel Disease: Navigating the Balance

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Authors

GDG D’ArcangeloSASilvana AnconaGCGiulia Catassi

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Overview

Critical review highlights risks of overtreatment and undertreatment in pediatric IBD, suggesting a need for better individualized treatment strategies.

Key Points

  • This research aims to identify the risks of overtreatment and undertreatment in pediatric inflammatory bowel disease (IBD) management.
  • Critical appraisal of current recommendations and evidence on pediatric IBD treatment
  • Analysis of risks related to overtreatment and undertreatment
  • Focus on individualized therapy versus generalized recommendations
  • Overtreatment can cause unnecessary adverse events in children with mild IBD, increasing psychosocial burdens.
  • Undertreatment in high-risk patients can result in ongoing inflammation and long-term complications.
  • A need for improvement in precision medicine to align treatment with individual disease biology is evident.

Cite This Study

D’Arcangelo et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf57cfaef96ed7f0577f8https://doi.org/10.1007/s40272-026-00751-8
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  5. 5Partial Enteral Nutrition in the Management of Crohn’s Disease: A Systematic Review and Meta-Analysis2024 · 25 citations