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June 14, 2026CancersOpen Access

Intraoperative Nodule Localization in Non-Small-Cell Lung Cancer: Existing and Emerging Techniques

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Authors

AAAidan AicherJTJerica TidwellSSSunil Singhal

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Overview

Review examines techniques for nodule localization in lung cancer, suggesting improved targeting methods for better outcomes.

Key Points

  • This review aims to explore existing and new techniques for localizing lung nodules during surgery.
  • Review of preoperative and intraoperative nodule localization techniques.
  • Comparison of efficacy and safety data for various localization modalities.
  • Analysis of emerging intraoperative molecular imaging approaches and their clinical trials.
  • Emerging techniques show promise in improving the accuracy of nodule localization.
  • Intraoperative imaging methods, including cone-beam CT, may enhance surgical outcomes.
  • Novel agents in clinical trials highlight advancements in molecular imaging for lung cancer.

Cite This Study

Aicher et al. (2026) studied this question.

synapsesocial.com/papers/6a2e472bb1cc60ccdea8bcb6https://doi.org/10.3390/cancers18121915
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preoperative and Intraoperative Localization of Small Pulmonary Nodules for Sublobar Resection: Practical Insights into Percutaneous, Bronchoscopic/Robotic, RFID (SuReFInD), and Hybrid-OR CT Workflows2026 · 1 citations
  2. 2Robotic-assisted bronchoscopic localization for small pulmonary nodules: a novel approach to minimally invasive surgery2025 · 2 citations
  3. 3Clinical application of CT-assisted body surface localization combined with intraoperative stereotactic anatomical localization in thoracoscopic lung nodule resection: a single-centre retrospective study2024
  4. 4Precision at the Margin: Innovations and Challenges in Intraoperative Molecular Imaging for Thoracic Surgery2026
  5. 5[Research Progress on Localization of Pulmonary Nodules].2024