Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 14, 2026动物学研究Open Access

产ndm-5的国际高风险克隆st410型大肠杆菌在国内动物医院的暴发与传播

View Full Paper
Ask AI
Bookmark
Share

Authors

CZCai Zhong-Peng151华南农业大学兽医学院 广东 广州 510642ZBZhu Bing-Qing

Discussion

Loading...

Member takes

Overview

Randomized trial investigates NDM-5 E. coli ST410 spread in animal hospitals, indicating public health risks.

Key Points

  • This research aims to analyze the prevalence and transmission dynamics of NDM-5 positive E. coli ST410 in companion animals across multiple veterinary hospitals in China.
  • Collected fecal and environmental samples from 12 companion animal hospitals in China from 2019 to 2025
  • Identified and analyzed 41 blaNDM-5 positive E. coli isolates, predominantly ST410 subtype
  • Conducted phylogenetic analysis of E. coli strains from pets and humans to assess genetic relationships
  • 36 out of 41 isolates (87.8%) were identified as sequence type 410 (ST410) with limited genomic diversity
  • Findings revealed substantial genetic similarity (≤25 cgSNPs) between pet-derived and human-derived ST410 isolates
  • Identified novel plasmids, including a blaNDM-5-carrying IncHI2-IncY plasmid in companion animals

Cite This Study

Zhong-Peng et al. (2026) studied this question.

synapsesocial.com/papers/6a2e4779b1cc60ccdea8bfc7https://doi.org/10.24272/j.issn.2095-8137.2025.363
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human Cases of Carbapenemase-Producing <i>Escherichia coli</i> Linked to Spread Between Animals and the Environment in a Veterinary Facility -Massachusetts, USA, 20232025 · 8 citations
  2. 2Emergence of NDM-producing Enterobacterales infections in companion animals from Argentina2024 · 11 citations
  3. 3Heterogeneity of plasmids containing OXA-48-like and NDM-5 carbapenemases and emergence of OXA-181 and NDM-5 co-carrying strains and plasmids in Escherichia coli from veterinary settings.2026
  4. 4Transmission chains and molecular characterizations of extended-spectrum β-lactamase producing Enterobacteriaceae at a veterinary hospital in Chengdu, China2024
  5. 5Monitoring antimicrobial resistance trends and emerging carbapenemases in Enterobacterales causing companion animal infections: a four-year study2026