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June 15, 2026Microbial Cell FactoriesOpen Access

Metabolomic insights into functional protein mediated salt stress adaptation in the osmophilic yeast Zygosaccharomyces rouxii

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Authors

DWDingkang WangLLLerong LiuSLS Liu

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Overview

Randomized trial explores metabolic responses to salt stress in Zygosaccharomyces rouxii, indicating improved adaptation with functional protein supplementation.

Key Points

  • This study aims to uncover the metabolic mechanisms that allow Zygosaccharomyces rouxii to adapt to high salt stress, particularly with functional protein supplementation.
  • Utilized an untargeted UPLC-HRMS-based metabolomics approach
  • Performed multivariate analysis to examine metabolic changes at 120 g/L NaCl
  • Conducted pathway enrichment analysis on metabolic responses to salt stress and protein supplementation.
  • Metabolic reprogramming was observed at high salt levels (120 g/L NaCl)
  • Functional protein supplementation enhanced amino acid metabolism and antioxidant-related pathways
  • Regulated pathways related to unsaturated fatty acids indicated improved membrane flexibility under stress.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a2f97e8a1cfeec490828e85https://doi.org/10.1186/s12934-026-03018-6
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