December 1, 1976Journal of Applied Physiology
Ventricular dimensions measured noninvasively by echocardiography in the awake dog
Key result
Surface echocardiography successfully measured left ventricular dimensions in awake dogs, with diastolic diameters averaging 3.7 cm and systolic diameters averaging 2.6 cm.
Why the study?
Does surface echocardiography accurately measure left ventricular dimensions in awake dogs compared to indicator-dilution curves and postmortem examination?
Population
37 awake mongrel dogs
Comparison
Surface echocardiography using intracardiac… vs Indicator-dilution curves and postmortem…
Design
Preclinical
Authors
Discussion
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Implication
Feasible for LV assessment in awake dogs; extends noninvasive options in canine models but leaves open clinical translation.
Study Design
Type
Observational (n=37)
Structured PICO
Does surface echocardiography accurately measure left ventricular dimensions in awake dogs compared to indicator-dilution curves and postmortem examination?
P
Population
37 awake mongrel dogs evaluated for left ventricular dimensions using surface echocardiography.
E
Exposure
Surface echocardiography using intracardiac bolus injections of dextran as echo contrast material
C
Comparator
Indicator-dilution curves (for stroke volume in 16 dogs) and postmortem examination (for structure identification)
O
Outcome
Left ventricular dimensions (end-diastolic and end-systolic diameters) and stroke volumesurrogate
Surface echocardiography is a feasible and reproducible noninvasive method for evaluating left ventricular dimensions in awake dogs.
Cite This Study
Mashiro et al. (1976) conducted an observational in Awake dogs (n=37). Surface echocardiography vs. Indicator-dilution curves was evaluated on Left ventricular dimensions. Surface echocardiography successfully measured left ventricular dimensions in awake dogs, with diastolic diameters averaging 3.7 cm and systolic diameters averaging 2.6 cm.