Key result
Isolation of a cDNA clone from human fibroblasts encoding a muscle-type tropomyosin suggests it and skeletal muscle beta-tropomyosin derive from a common gene via alternative RNA splicing.
Authors
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Highlights tropomyosin isoform diversity in non-muscle cells; leaves open cardiac functional and therapeutic implications.
Key points are not available for this paper at this time.
MacLeod et al. (1985) studied this question. Isolation of a cDNA clone from human fibroblasts encoding a muscle-type tropomyosin suggests it and skeletal muscle beta-tropomyosin derive from a common gene via alternative RNA splicing.
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