Key result
The sequence of a 2.5 kb mRNA in human fibroblasts encoding TM30nm, a 248 amino acid cytoskeletal tropomyosin, was determined, revealing tissue-specific alternative mRNA splicing.
Authors
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Highlights tropomyosin splicing diversity in fibroblasts; extends molecular characterization but leaves clinical relevance open.
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MacLeod et al. (1986) studied this question. The sequence of a 2.5 kb mRNA in human fibroblasts encoding TM30nm, a 248 amino acid cytoskeletal tropomyosin, was determined, revealing tissue-specific alternative mRNA splicing.
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