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September 1, 2015Open Access

Acute kidney injury after transcatheter aortic valve implantation.

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Population

High-risk patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI)

Design

Review

Authors

MSMaximilian SchernerDüsseldorf University HospitalTWThorsten WahlersCardiac Surgery

Discussion

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Overview

AKI after TAVI warrants vigilant monitoring given its mortality link; leaves open optimal prevention strategies in prospective trials.

Structured PICO

P
Population
High-risk patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI)
I
Intervention
Transcatheter aortic valve implantation (TAVI)
O
Outcome
Acute kidney injury (AKI) and its impact on mortalitysafety

Acute kidney injury is a common and serious complication after TAVI that significantly impacts mortality, highlighting the need for standardized definitions (VARC-2) and careful periprocedural management to mitigate risk factors like blood transfusions.

Limitations

  • Lack of standardization with regard to the definition of AKI in current studies complicates interpretation
  • Inability of most studies to determine if the relation between increased contrast media and worse post-TAVI outcomes is associative or causative

Cite This Study

Scherner et al. (2015) studied this question.

synapsesocial.com/papers/6a323558cf42d9fde8ddca1bhttps://doi.org/10.3978/j.issn.2072-1439.2015.06.14
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blood Transfusion and the Risk of Acute Kidney Injury After Transcatheter Aortic Valve Implantation2012 · 145 citations
  2. 2Prognostic Value of Chronic Kidney Disease After Transcatheter Aortic Valve Implantation2013 · 173 citations
  3. 3Predictors and outcomes after transcatheter aortic valve implantation using different approaches according to the valve academic research consortium definitions2012 · 66 citations
  4. 4Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium2011 · 1,224 citations
  5. 5A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention2004 · 2,047 citations