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June 17, 2026Open Access

Efficacy and Safety of Polyherbal Formulations in the Management of Primary Dysmenorrhea: A Systematic Review

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Authors

MKMs. Jannat Diwate*1, Dr. Shailesh Patwekar2, Mr. Shubham Kamdi3, Ms. Pallavi Gondale4, Ms. Rutuja Patil5, Ms. Shreya Kadam6

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Overview

Systematic review evaluates herbal alternatives for primary dysmenorrhea, suggesting effective and safer options.

Key Points

  • To evaluate the efficacy and safety of herbal and polyherbal treatments for primary dysmenorrhea.
  • Conducted a systematic review following PRISMA 2020 guidelines.
  • Searched electronic databases for RCTs published until April 2026.
  • Included studies on women with primary dysmenorrhea treated with herbal interventions.
  • Sixteen RCTs with 1,641 participants were included in the review.
  • Most studies showed significant reductions in menstrual pain compared to placebo.
  • Adverse effects were mild, infrequent, and primarily gastrointestinal.

Cite This Study

Ms. Jannat Diwate*1, Dr. Shailesh Patwekar2, Mr. Shubham Kamdi3, Ms. Pallavi Gondale4, Ms. Rutuja Patil5, Ms. Shreya Kadam6 (2026) studied this question.

synapsesocial.com/papers/6a323bbcd50b63ecad2062fchttps://doi.org/10.5281/zenodo.20696379
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1EFFICACY AND SAFETY OF POLYHERBAL FORMULATIONS IN THE MANAGEMENT OF PRIMARY DYSMENORRHEA: A SYSTEMATIC REVIEW2026
  2. 2Efficacy of Plant‐Derived Therapies for Primary Dysmenorrhea: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials2026
  3. 3A Review of In Vitro and In Vivo Studies on the Efficacy of Herbal Medicines for Primary Dysmenorrhea2014 · 25 citations
  4. 4The Effect of Ginger, Cinnamon, and Fennel on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis2025
  5. 5Efficacy of a Standardized Ginger Extract for Menstrual Pain and Associated Symptoms in Women With Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Trial2026