What question did this study set out to answer?

To review preclinical in vitro and in vivo studies evaluating the efficacy and underlying biological mechanisms of herbal medicines for primary dysmenorrhea.

January 1, 2014Evidence-based Complementary and Alternative MedicineOpen Access

A Review of In Vitro and In Vivo Studies on the Efficacy of Herbal Medicines for Primary Dysmenorrhea

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Authors

KPKyoung-Sun ParkKyung Hee University KPKang-In ParkKyung Hee University DHDeok‐Sang HwangKyung Hee University

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Implication

Literature review demonstrates herbal medicines reduce pain and uterine contractions in primary dysmenorrhea models, suggesting potential therapeutic value.

Key Points

To review preclinical in vitro and in vivo studies evaluating the efficacy and underlying biological mechanisms of herbal medicines for primary dysmenorrhea.
Reviewed in vitro and in vivo preclinical studies evaluating individual herbal extracts, isolated compounds, or herbal formula decoctions published up to April 2014.
A total of 18 preclinical studies demonstrated significant inhibitory effects of herbal medicines on primary dysmenorrhea, notably suppressing uterine contractions in vitro.
In vivo analyses showed peripheral analgesia and anti-inflammatory activity driven by the reduction of prostaglandin synthesis, cyclooxygenase-2, inducible nitric oxide synthase, nuclear factor-kappa B, intracellular calcium, and malondialdehyde, alongside superoxide dismutase activation.

Cite This Study

Park et al. (2014) studied this question.

synapsesocial.com/papers/6a901ced55a9abd3b0840324 https://doi.org/10.1155/2014/296860

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Implication

Literature review demonstrates herbal medicines reduce pain and uterine contractions in primary dysmenorrhea models, suggesting potential therapeutic value.

A Review of In Vitro and In Vivo Studies on the Efficacy of Herbal Medicines for Primary Dysmenorrhea

Discussion

Member takes

Implication

Key Points

Cite This Study

A Review of In Vitro and In Vivo Studies on the Efficacy of Herbal Medicines for Primary Dysmenorrhea

Discussion

Member takes

Implication

Key Points

Cite This Study

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