Key result
Coronary angiography inaccurately estimated the degree of left main coronary artery narrowing in 71% (20 of 28) of patients when compared to necropsy findings.
Why the study?
Does coronary angiography accurately determine the degree of left main coronary arterial narrowing compared to necropsy in patients with symptomatic coronary heart disease?
Population
28 patients with symptomatic coronary heart disease in whom angiography had been performed within 40 days of…
Comparison
Coronary angiography evaluated independently by… vs Necropsy
Design
Cross-sectional, Evaluated independently by three experienced angiographers
Follow-up
within 40 days of death
Authors
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Angiographic left main assessment may be unreliable; supports clinical caution and leaves open validation of adjunctive imaging.
Cross-Sectional (n=28)
Does coronary angiography accurately determine the degree of left main coronary arterial narrowing compared to necropsy in patients with symptomatic coronary heart disease?
Angiographic determination of left main coronary artery narrowing is subject to considerable error, frequently underestimating or overestimating the true histologic severity.
Isner et al. (1981) conducted a cross-sectional in Symptomatic coronary heart disease (n=28). Coronary angiography vs. Necropsy (histologic determination) was evaluated on Accuracy of coronary angiography in identifying severe narrowing of the left main coronary artery. Coronary angiography inaccurately estimated the degree of left main coronary artery narrowing in 71% (20 of 28) of patients when compared to necropsy findings.
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