Key result
High physical activity in childhood cancer survivors was associated with lower percent fat mass (24.4% vs. 29.8%, P<0.0001) and improved body composition compared to low physical activity.
Why the study?
Does high physical activity improve cardiovascular risk factors in childhood cancer survivors?
Population
319 childhood cancer survivors (CCS) and 208 sibling controls aged 9–18 years
Comparison
High physical activity (≥60 min/day) vs Low physical activity and sibling controls
Design
Cross-sectional
Authors
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May support activity promotion trials in survivors; leaves open causal CVD benefits without RCTs.
Cross-Sectional (n=527)
Does high physical activity improve cardiovascular risk factors in childhood cancer survivors?
Absolute Event Rate: 24.4% vs 29.8%
p-value: p=<0.0001
High physical activity in childhood cancer survivors is associated with an improved cardiovascular risk profile, primarily through lower fat mass and greater lean mass.
Slater et al. (2014) conducted a cross-sectional in Childhood cancer survivors (n=527). High physical activity (≥60 min/day) vs. Low physical activity (<60 min/day) was evaluated on Percent fat mass (p=<0.0001). High physical activity in childhood cancer survivors was associated with lower percent fat mass (24.4% vs. 29.8%, P<0.0001) and improved body composition compared to low physical activity.
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