Key result
Excessive left ventricular hypertrophy disproportionate to left ventricular afterload in patients with aortic stenosis is associated with higher cardiovascular morbidity and mortality.
This review challenges the traditional view of left ventricular hypertrophy as a purely beneficial compensatory mechanism in aortic stenosis, highlighting its association with adverse outcomes when excessive.
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Questions LVH as purely adaptive in aortic stenosis; leaves open whether regression improves outcomes.
Davies et al. (2018) conducted a review in Aortic stenosis and left ventricular hypertrophy. Excessive left ventricular hypertrophy vs. Appropriate or absent left ventricular hypertrophy was evaluated. Excessive left ventricular hypertrophy disproportionate to left ventricular afterload in patients with aortic stenosis is associated with higher cardiovascular morbidity and mortality.
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