Key result
Maximal oxygen uptake (VO2max) in healthy subjects appears limited by the supply of oxygen to the mitochondria, depending on integrated diffusive and convective steps in the oxygen pathway.
Why the study?
Is maximal oxygen uptake (VO2max) during exercise in healthy subjects limited by the supply of oxygen to muscle mitochondria?
Population
Healthy subjects during exercise
Design
Review
Authors
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Supports supply-limited VO2max in healthy subjects; leaves open utilization constraints and disease applications.
Is maximal oxygen uptake (VO2max) during exercise in healthy subjects limited by the supply of oxygen to muscle mitochondria?
This review supports the hypothesis that maximal oxygen uptake during exercise in healthy individuals is primarily limited by oxygen supply to the mitochondria rather than biochemical utilization limits.
Peter D. Wagner (1995) conducted a review in Healthy subjects. Maximal oxygen uptake (VO2max) in healthy subjects appears limited by the supply of oxygen to the mitochondria, depending on integrated diffusive and convective steps in the oxygen pathway.
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