Key result
In NVAF patients with mildly impaired renal function and recurrent arrhythmia after catheter ablation, mean eGFR significantly increased from 78.0 at baseline to 81.5 ml/min/1.73 m2 (P<0.001).
Why the study?
Renal function in patients with recurrence of AF after catheter ablation had not been studied separately, despite known improvements after successful ablation.
Does catheter ablation improve renal function in nonvalvular AF patients with mildly impaired renal function who experience atrial arrhythmia recurrence?
Cohort (n=132)
Does catheter ablation improve renal function in nonvalvular AF patients with mildly impaired renal function who experience atrial arrhythmia recurrence?
Absolute Event Rate: 81.5% vs 78%
p-value: p=< 0.001
Catheter ablation for atrial fibrillation is associated with improved renal function in patients with mild baseline renal impairment, even among those who experience arrhythmia recurrence.
No takes yet. Share an insight, caveat, or question.
eGFR rise after ablation despite recurrent arrhythmia may indicate renal benefit in mild impairment; hypothesis-generating, needs prospective confirmation.
Shen et al. (2022) conducted a cohort in Nonvalvular atrial fibrillation with mildly impaired renal function and recurrence after ablation (n=132). Catheter ablation vs. Baseline (pre-ablation) was evaluated on Improved renal function (△eGFR >0) after AF catheter ablation in patients with atrial arrhythmia recurrence (p=< 0.001). In NVAF patients with mildly impaired renal function and recurrent arrhythmia after catheter ablation, mean eGFR significantly increased from 78.0 at baseline to 81.5 ml/min/1.73 m2 (P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: