Key result
Freedom from arrhythmia after catheter ablation of atrial fibrillation was associated with improved eGFR over 1 year compared with arrhythmia recurrence (3 vs -2 mL/min/1.73 m2; P<0.0001).
Why the study?
Does successful elimination of atrial fibrillation by catheter ablation improve kidney function in patients with mild to moderate kidney dysfunction?
Cohort (n=386)
Does successful elimination of atrial fibrillation by catheter ablation improve kidney function in patients with mild to moderate kidney dysfunction?
Absolute Event Rate: 3% vs -2%
p-value: p=<0.0001
Successful elimination of atrial fibrillation via catheter ablation is associated with a significant improvement in kidney function at 1 year in patients with mild to moderate kidney dysfunction.
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May support renal benefit from successful AF ablation in mild-moderate CKD; hypothesis-generating and requires randomized confirmation before practice change.
Takahashi et al. (2011) conducted a cohort in Atrial fibrillation (n=386). Freedom from arrhythmia after catheter ablation vs. Arrhythmia recurrence was evaluated on Changes in estimated glomerular filtration rate (eGFR) over 1 year (p=<0.0001). Freedom from arrhythmia after catheter ablation of atrial fibrillation was associated with improved eGFR over 1 year compared with arrhythmia recurrence (3 vs -2 mL/min/1.73 m2; P<0.0001).
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