PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 1, 2006Medicine & Science in Sports & Exercise40 citations

The Influence of Menstrual Cycle Phase upon Postexercise Hypotension

View Full Paper
JEJoseph I. EsformesFNFrances NormanJSJoanne Sigley

Key Result

Menstrual cycle phase did not affect the pattern of postexercise hypotension, though diastolic pressure dropped significantly lower in the early follicular phase (P < 0.05).

Study Design

Type

Observational (n=8)

Structured PICO

Does menstrual cycle phase influence postexercise hypotension in eumenorrheic women?

P
Population
8 eumenorrheic women evaluated for postexercise hypotension across early follicular, late follicular, and midluteal phases following 30 minutes of exercise.
E
Exposure
30 min of exercise at 80% lactate threshold evaluated during early follicular (EF), late follicular (LF), and midluteal (ML) phases
C
Comparator
Comparison between menstrual cycle phases (EF, LF, ML) and rest
O
Outcome
Pattern of postexercise hypotension (PEH) and blood pressure over 45 min post-exercisesurrogate

Postexercise hypotension is more pronounced in the early follicular phase compared to the late follicular and midluteal phases, suggesting enhanced buffering of PEH when estrogen levels are elevated.

Main Result

p-value: p=<0.05

Abstract

PURPOSE: Postexercise hypotension (PEH) has been observed in males and females; however, the impact of menstrual cycle phase upon PEH has not been evaluated. We examined the pattern of PEH in the early follicular (EF), late follicular (LF), and midluteal (ML) phases of the menstrual cycle in eight eumenorrheic women following 30 min of exercise at 80% lactate threshold. METHODS: Supine hemodynamic measurements were assessed at rest and then for 45 min following exercise. Blood pressure was measured with manual sphygmomanometry, calf vascular resistance (CVR) via venous occlusion plethysmography, and central hemodynamics with echocardiography. RESULTS: Cardiovascular parameters did not differ between menstrual phases at rest (P > 0.05). The pattern of PEH was unaffected by menstrual phase, but mean arterial and diastolic (DBP) pressures dropped to significantly lower levels across the recovery period in the EF phase than in the LF and ML phases (mean DBP EF: 69 +/- 4; LF 74 +/- 3; ML 72 +/- 5; P 0.05). These parameters, except for left ventricular dimensions in systole and heart rate, varied with recovery time, increasing to a peak between 5 and 10 min postexercise (P < 0.05). CVR displayed a significant interaction between cycle phase and recovery time as resistance increased to greater values in the ML phase compared with the EF and LF phases following 30 min of postexercise recovery (P < 0.05). CONCLUSION: Buffering of PEH appears to be enhanced in the LF and ML phases of the cycle where estrogen concentrations are known to be elevated.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Esformes et al. (2006) conducted an observational in Postexercise hypotension (n=8). Menstrual cycle phase vs. Comparison between early follicular, late follicular, and midluteal phases was evaluated on Postexercise blood pressure and hemodynamics (p=<0.05). Menstrual cycle phase did not affect the pattern of postexercise hypotension, though diastolic pressure dropped significantly lower in the early follicular phase (P < 0.05).

synapsesocial.com/papers/6a33810113060137255e94f1https://doi.org/10.1249/01.mss.0000193559.98095.ea
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Estrogen enhancement of baroreflex sensitivity is centrally mediated1999 · 104 citations
  2. 2Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.1977 · 4,509 citations
  3. 3Mechanisms and Clinical Implications of Post-exercise Hypotension in Humans2001 · 187 citations
  4. 4Postexercise hypotension is mediated by reductions in sympathetic nerve activity1999 · 139 citations
  5. 5Post-exercise changes in blood pressure, heart rate and rate pressure product at different exercise intensities in normotensive humans1998 · 188 citations