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Investigates cell free DNA in pleural disease, suggesting enhanced detection in lung cancer.
Cell free DNA in pleural diseasePlasma circulating tumour DNA (ctDNA) has a low detection rate for isolated malignant pleural effusion (MPE) in non-small cell lung cancer (NSCLC).Pleural fluid cell free DNA (cfDNA) detects all extracellular DNA fragments, not limited to DNA from tumour cells, and may improve detection rates.
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