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Evaluate the efficacy of 820 nm diode laser combined with methylene blue to enhance open wound healing in rats.

Use of 820 nm Diode Laser Conjugating With Methylene Blue to Improve Open Wound Healing in Rats

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Evaluate the efficacy of 820 nm diode laser combined with methylene blue to enhance open wound healing in rats.
Divided 60 male Wistar rats into 4 groups: control, laser treatment, methylene blue treatment, combined treatment.
Applied laser treatment of 8J/cm²/day for 7 days, and methylene blue topically for 5 min/day for 7 days.
Assessed wound healing through gross and microscopic evaluations over 21 days.
Significantly reduced wound size in treated groups at 7 and 14 days (P < 0.05 compared to control).
Epithelialization period was 8-10 days for treated groups, compared to 8 days for control.
G4 group showed complete re-epithelialization by day 7, with improved granulation tissue and collagen arrangement.

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Randomized trial evaluates improved wound healing in rats using laser and methylene blue, highlighting effectiveness.

Abid et al. (2022) studied this question.

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