Turmeric extract ointment and diode laser for treatment of open wound
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Key Points
The study aims to evaluate the effects of 20% turmeric extract ointment combined with diode laser therapy on open wound healing.
Utilized 30 adult male mice, randomly divided into control and treatment groups.
Control group received no treatment, while the treatment group received 200 mg/cm² of turmeric extract ointment and diode laser therapy for 7 days post-wounding.
Wounds were assessed grossly and histopathologically at 7, 14, and 21 days post-wounding.
At 7 and 14 days, treated wounds were significantly smaller (P < 0.05) than control wounds.
Histopathology revealed better reepithelialization and collagen formation in the treatment group compared to controls at all time points.
At 21 days, treated wounds showed well-organized epidermal layers and dermis with numerous hair follicles and mature collagen.
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Implication
Randomized trial evaluates turmeric extract and laser therapy effectiveness on open wounds in mice, suggesting improved healing outcomes.