Key result
Mitral E/Ea ratio strongly correlates with invasive PCWP to noninvasively estimate LV filling pressures.
Why the study?
Recent observations suggested mitral annular Ea reflects LV relaxation less influenced by filling pressures, prompting investigation into whether Ea is preload-independent and whether E/Ea relates to LV filling pressures.
Does the E/Ea ratio derived from Doppler tissue imaging accurately estimate left ventricular filling pressures?
Cross-Sectional (n=125)
Does the E/Ea ratio derived from Doppler tissue imaging accurately estimate left ventricular filling pressures?
The E/Ea ratio derived from Doppler tissue imaging is a reliable, noninvasive index for estimating left ventricular filling pressures.
Answers are grounded in this paper and cite their sources.
May aid noninvasive LV filling pressure estimation; leaves open prospective validation before routine adoption.
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Nagueh et al. (1997) conducted a cross-sectional in Left ventricular diastolic dysfunction (n=125). Doppler tissue imaging (E/Ea ratio) vs. Invasive pulmonary capillary wedge pressure (PCWP) was evaluated on Correlation between E/Ea ratio and PCWP (r = 0.87). The mitral E/Ea ratio derived from Doppler tissue imaging correlated strongly with invasive pulmonary capillary wedge pressure (r = 0.87), allowing noninvasive estimation of LV filling pressures.
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