Key result
Tissue Doppler E/E' ratio strongly correlates with invasive LVEDP in systolic and diastolic heart failure.
Why the study?
Noninvasive assessment of diastolic filling by Doppler echocardiography requires validation against invasive measures of diastolic LV performance in patients with systolic and diastolic heart failure.
Does lateral mitral annular E/E' by tissue Doppler imaging accurately estimate invasive LVEDP in patients with systolic and diastolic heart failure?
Population
100 patients undergoing diagnostic coronary angiogram including 50 with diastolic and 50 with systolic heart failure
Comparison
Lateral mitral annular E/E′ by tissue Doppler imaging vs invasive LVEDP measurement
Design
Cross-sectional study
Authors
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May support noninvasive LVEDP estimation in HF; hypothesis-generating and requires prospective validation before clinical use.
Cross-Sectional (n=100)
No
Does lateral mitral annular E/E' by tissue Doppler imaging accurately estimate invasive LVEDP in patients with systolic and diastolic heart failure?
Effect estimate: r=0.79
p-value: p=<0.0001
Lateral mitral annular E/E' by tissue Doppler imaging is a reliable noninvasive estimate of left ventricular filling pressures in patients with both systolic and diastolic heart failure.
Suranagi et al. (2020) conducted a cross-sectional in Systolic and diastolic heart failure (n=100). Tissue Doppler Imaging (E/E' ratio) vs. Invasive LVEDP measurement was evaluated on Correlation between E/E' and invasive LVEDP (r=0.79, p=<0.0001). The E/E' ratio by tissue Doppler imaging correlated significantly with invasive left ventricular end-diastolic pressure (r=0.79, p<0.0001) in both systolic and diastolic heart failure patients.
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