Why the study?
Does the deceleration time of early mitral annular velocity (e'DT) accurately predict elevated left ventricular end-diastolic pressure in patients with heart failure?
Population
94 patients admitted to the hospital for heart failure. Exclusion criteria: atrial fibrillation, mitral…
Comparison
Measurement of deceleration time of early mitral… vs Simultaneous invasive left ventricular…
Design
Cross-sectional
Key result
The deceleration time of early mitral annular velocity (e'DT) predicted LVEDP >16 mm Hg with a significantly greater area under the curve than E/e' (0.91 vs 0.74, P=0.046).
Authors
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e'DT may better estimate elevated LVEDP than E/e' in HF; hypothesis-generating and requires prospective validation.
Observational (n=94)
Does the deceleration time of early mitral annular velocity (e'DT) accurately predict elevated left ventricular end-diastolic pressure in patients with heart failure?
Absolute Event Rate: 0.91% vs 0.74%
p-value: p=0.046
The deceleration time of early mitral annular velocity (e'DT) is a simple and accurate noninvasive index for estimating LV filling pressure, outperforming E/e', particularly in patients with an intermediate E/e' of 10-14.
Takemoto et al. (2017) conducted an observational in Heart failure (n=94). Deceleration time of early mitral annular velocity (e'DT) vs. Early transmitral flow velocity (E)/e' was evaluated on Prediction of LVEDP >16 mm Hg (Area under the ROC curve) (p=0.046). The deceleration time of early mitral annular velocity (e'DT) predicted LVEDP >16 mm Hg with a significantly greater area under the curve than E/e' (0.91 vs 0.74, P=0.046).