Key result
PTCA outpaces CABG in ~58% of revascularizations, except in triple-vessel or left main disease.
Why the study?
CAD prevalence is rising rapidly in India, but limited information exists regarding clinical characteristics of patients currently undergoing coronary revascularization.
Observational (n=2,847)
No
Absolute Event Rate: 58.1% vs 41.9%
In a contemporary North Indian cohort, PTCA is the preferred mode of revascularization overall, whereas CABG remains preferred for complex disease such as triple-vessel or left main CAD.
PTCA predominates in this North Indian revascularization cohort; extends prior observations but leaves open optimal strategy selection in complex disease.
A BSTRACT Background: Coronary artery disease (CAD) is among the leading causes of death worldwide, and its prevalence is rising rapidly in India. Revascularization is an important mode of treatment for CAD. Unfortunately, only limited information is available regarding the clinical characteristics of the patients currently undergoing coronary revascularization in India. Methods: This was a retrospective study conducted at a premier, tertiary care center in North India. A total of 2847 consecutive subjects (mean age 61.3 ± 10.3 years, 2374 [83.4%] men) undergoing coronary revascularization were included. Results: Overall, percutaneous transluminal coronary angioplasty (PTCA) was a more common mode of coronary revascularization than coronary artery bypass graft surgery (CABG) (58.1% vs. 41.9% of patients). Although there was a higher usage of CABG among males, older patients, patients with diabetes mellitus (DM), and those presenting with stable CAD, PTCA was still the preferred mode of revascularization. Only in patients with triple-vessel CAD or left main CAD, CABG was performed more commonly than PTCA (64.7% vs. 35.3% for triple-vessel disease and 81.4% vs. 18.6% for left main disease). When compared with a previous group of 1000 patients who had undergone CABG in the year 2004, the patients in the current cohort were older, had less hypertension but a higher prevalence of DM, and had lower levels of total cholesterol and low-density lipoprotein cholesterol. Conclusion: Our study describes the clinical profile of patients currently undergoing coronary revascularization in North India. The study showed that PTCA was the preferred mode of coronary revascularization in most patients, except in those with triple-vessel CAD or left main CAD. Compared with the PTCA patients, those undergoing CABG had a consistently higher prevalence of diabetes, across all clinical subgroups. Further prospective studies are required to determine the long-term clinical implications of these findings.
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Bansal et al. (2025) conducted an observational in Coronary artery disease (n=2,847). Percutaneous transluminal coronary angioplasty (PTCA) vs. Coronary artery bypass graft surgery (CABG) was evaluated on Mode of coronary revascularization. Percutaneous transluminal coronary angioplasty was the preferred mode of revascularization over CABG overall (58.1% vs. 41.9%), except in patients with triple-vessel or left main disease.
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