Key result
Transthoracic echocardiography using pulsed Doppler at the aortic annulus accurately assessed cardiac output in rats compared to thermodilution (r = 0.93; P < 0.0001, bias -3 ml/min).
Why the study?
Does transthoracic echocardiography accurately measure cardiac output compared to thermodilution in rats?
Does transthoracic echocardiography accurately measure cardiac output compared to thermodilution in rats?
Effect estimate: r = 0.93
p-value: p=< 0.0001
Transthoracic echocardiography using pulsed Doppler at the aortic annulus provides accurate and precise measurements of cardiac output in rats compared to thermodilution.
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Supports echo CO assessment in rat models; leaves open translation to clinical or larger-animal studies.
Slama et al. (2003) studied this question. Transthoracic echocardiography (pulsed Doppler at aortic annulus) vs. Thermodilution was evaluated on Correlation of cardiac output measurement between echocardiography and thermodilution (r = 0.93, p=< 0.0001). Transthoracic echocardiography using pulsed Doppler at the aortic annulus accurately assessed cardiac output in rats compared to thermodilution (r = 0.93; P < 0.0001, bias -3 ml/min).
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