Based on the G₀ framework, lifespan model and equilibrium zero-tolerance principle of the preceding three papers, this paper puts forward the Localized Isolation Barrier Principle for irreparable system damage. Combined with the state equation: G = G₀ + ΔGd (+) − ΔGd (−) and dissipation limit: ε (T) = o (1/T) we demonstrate that biological tumor fibrous encapsulation and electronic circuit fault isolation are isomorphic emergency protection strategies. When damage exceeds repair capacity, the system builds a physical/logical barrier to confine harm within a local range, preventing unlimited growth of residual dissipation. Tumor tissue is a systemic stress protection response rather than an absolute pathogenic source; localized isolation effectively controls ε (T), slows quota Q consumption and extends overall system lifespan L = Q / C. This theory corrects one-sided understanding of tumors and circuit faults, unifying pathology and electronic reliability engineering.
FOO SENG ANG (Sat,) studied this question.