Monogenic atrial fibrillation as pathophysiological paradigms
Key result
This review highlights that while monogenic forms of atrial fibrillation are rare, identifying their mutations provides valuable insights into the molecular pathways underlying the arrhythmia.
Population
Patients with atrial fibrillation, with a focus on monogenic and familial forms as well as typical forms in…
Design
Review
Authors
Discussion
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Implication
Monogenic AF insights extend pathway knowledge; leaves open targeted interventions for common forms.
Structured PICO
P
Population
Patients with atrial fibrillation, with a focus on monogenic and familial forms as well as typical forms in the general population
Understanding the genetic substrate of monogenic and typical forms of atrial fibrillation may lead to novel diagnostic tools and targeted rhythm control strategies.
Cite This Study
Mahida et al. (2010) conducted a review in Atrial fibrillation. Monogenic forms of atrial fibrillation was evaluated. This review highlights that while monogenic forms of atrial fibrillation are rare, identifying their mutations provides valuable insights into the molecular pathways underlying the arrhythmia.