Key result
Subpectoral pocket revision achieves ~75% device salvage in select CIED infections, avoiding explantation.
Why the study?
Complete CIED explantation for infection is expensive, technically demanding, carries complications, and may not be feasible in device-dependent patients.
Observational (n=12)
Subpectoral revision may salvage selected infected CIEDs without explantation; leaves open need for prospective trials before wider use.
Introduction Infection of cardiac implantable electrical devices (CIEDs) may lead to serious complications. Complete CIED explantation is expensive, requires expertise, not free from complications, and may not be an option in patients with device dependence. Aim To highlight that carefully selected infected CIEDs can be salvaged by placing the device in a subpectoral pocket below the pectoralis major muscle. We conducted a retrospective descriptive observational study. Material and Methods Twelve patients (10 male and two female) with erosion, exposure or infection of infraclavicular, subcutaneously placed CIED were treated over a 30-month period between July 2018 and December 2020. The technique involved debridement and excision of a peridevice capsule, creating a subpectoral pocket beneath the pectoralis major muscle, and placing the CIED in a new pocket with total muscle coverage and closure of skin without tension. Results Twelve patients (m = 10; f = 2) with a mean age of 65 years (range, 46–82 years) presented with infection of CIED within 9 months of implantation. None had sepsis or endocarditis. In nine patients, CIEDs were successfully salvaged with relocation to subpectoral pocket. Mean follow-up was 20 months (range, 8–30 months). Three out of 12 developed reinfection that ultimately required CIED explantation. There was no mortality. Conclusion In the absence of sepsis or endocarditis, infected CIEDs may be attempted at salvage by subpectoral pocket placement. This obviates the need for potentially risky explantation or replacement of expensive CIEDs.
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Chatterjee et al. (2021) conducted an observational in Localized infection, erosion, or exposure of cardiac implantable electrical devices (CIEDs) (n=12). Salvage with subpectoral pocket revision was evaluated on Successful device salvage. Salvage of infected or exposed cardiac implantable electrical devices via subpectoral pocket revision was successfully achieved in 75% (9 of 12) of carefully selected patients, avoiding explantation.
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