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May 1, 2001Archives of Neurology

Recurrence of Acute Disseminated Encephalomyelitis at the Previously Affected Brain Site

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Key result

Recurrent acute disseminated encephalomyelitis occurred in 24% (5 of 21) of patients, often involving the previously affected brain territory and showing a good response to corticosteroid therapy.

Why the study?

What is the frequency, nature, and outcome of recurrent acute disseminated encephalomyelitis?

Population

21 patients diagnosed with acute disseminated encephalomyelitis between January 1, 1983, and May 31, 1998

Design

Cohort

Authors

OCOren CohenMount Sinai HospitalBSBettina Steiner‐BirmannsShaare Zedek Medical CenterIBIftah BiranTel Aviv Sourasky Medical Center

Discussion

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Implication

May increase vigilance for ADEM recurrence; leaves open optimal prevention strategies in this small observational cohort.

Study Design

Type

Observational (n=21)

Multicenter

No

Structured PICO

What is the frequency, nature, and outcome of recurrent acute disseminated encephalomyelitis?

P
Population
21 patients diagnosed with acute disseminated encephalomyelitis (ADEM) at a single institution between 1983 and 1998.
E
Exposure
Corticosteroid therapy
O
Outcome
Frequency, nature, and outcome of recurrent ADEM

Recurrent ADEM may be more prevalent than previously recognized, often involving the same brain territory and responding well to corticosteroids.

Cite This Study

Cohen et al. (2001) conducted an observational in Acute disseminated encephalomyelitis (ADEM) (n=21). Acute disseminated encephalomyelitis was evaluated on Recurrent disease episodes. Recurrent acute disseminated encephalomyelitis occurred in 24% (5 of 21) of patients, often involving the previously affected brain territory and showing a good response to corticosteroid therapy.

synapsesocial.com/papers/6a3b1f16cc8dbc104a21bb5ehttps://doi.org/10.1001/archneur.58.5.797
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Post-Infectious Encephalomyelitis and Multiple Sclerosis1950 · 103 citations
  2. 2Therapeutic plasma exchange for acute inflammatory demyelinating syndromes of the central nervous system1999 · 44 citations
  3. 3ACUTE DISSEMINATED ENCEPHALOMYELITIS1990 · 394 citations
  4. 4MR Diagnosis of Acute Disseminated Encephalomyelitis1986 · 147 citations
  5. 5The Pathogenesis of Acute Viral Encephalitis and Postinfectious Encephalomyelitis1987 · 151 citations