Why the study?
Does concomitant carotid artery stenting reduce the composite of all-cause mortality, disabling stroke, and MACE at 1 year in patients with severe symptomatic aortic stenosis and carotid artery stenosis undergoing TAVI compared to conservative treatment?
Cohort (n=1,628)
Yes
Does concomitant carotid artery stenting reduce the composite of all-cause mortality, disabling stroke, and MACE at 1 year in patients with severe symptomatic aortic stenosis and carotid artery stenosis undergoing TAVI compared to conservative treatment?
Hazard Ratio: 0.64 (95% CI 0.48–0.87)
Absolute Event Rate: 2.1% vs 7.4%
p-value: p=<0.001
Concomitant carotid artery stenting during TAVI in patients with severe carotid artery stenosis is associated with a significantly lower risk of 1-year mortality, disabling stroke, and MACE compared to conservative management.
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Cammalleri et al. (2026) conducted a cohort in Severe symptomatic aortic stenosis and carotid artery stenosis (n=1,628). Carotid artery stenting (CAS) vs. Conservative treatment was evaluated on Composite of all-cause mortality, disabling stroke, and major adverse cardiovascular events (MACE) at 1 year (HR 0.64, 95% CI 0.48-0.87, p=<0.001).
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