Why the study?
Left ventricular dysfunction and thrombosis in unrepaired tetralogy of Fallot are rarely reported.
Surgical repair in a pediatric patient with unrepaired tetralogy of Fallot and severe biventricular dysfunction with LV thrombus led to recovery of ventricular function and thrombus resolution.
Suggests potential reversibility of dysfunction and thrombus after repair in unrepaired TOF; hypothesis-generating and should not yet change practice.
Left ventricular dysfunction and thrombosis in unrepaired tetralogy of Fallot are rarely reported. We report the case of a 9-year-old boy with unrepaired tetralogy of Fallot, severe biventricular dysfunction, large left ventricular thrombus, and diffuse subendocardial fibroelastosis. After surgical repair, recovery of ventricular function and thrombus resolution were observed. This case highlights the interplay between cyanosis, myocardial remodelling, and hypercoagulability and emphasises the role of multimodality imaging.
No takes yet. Share an insight, caveat, or question.
Cosola et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: