What question did this study set out to answer?

To highlight the atypical presentation of Hailey–Hailey disease that mimics other conditions, complicating diagnosis.

June 26, 2026Clinical Case ReportsOpen Access

Atypical Follicular–Pigmentary Variant of Hailey–Hailey Disease: A Diagnostic Dilemma

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This case describes an atypical diagnostic challenge of Hailey–Hailey disease in a male patient, emphasizing the need for proper identification.

To highlight the atypical presentation of Hailey–Hailey disease that mimics other conditions, complicating diagnosis.
Patient presentation of recurrent pruritic lesions over flexural regions examined for clinical manifestations.
Histopathological analysis conducted to identify the characteristics of the lesions.
Clinicopathological correlation established to finalize the diagnosis.
Diagnosis confirmed through histopathology showing suprabasal acantholysis with a specific pattern.
Atypical presentations identified, with papular forms mimicking other acantholytic dermatoses.
Recognition of morphological variations essential for accurate diagnosis.

Shah et al. (2026) studied this question.

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This case describes an atypical diagnostic challenge of Hailey–Hailey disease in a male patient, emphasizing the need for proper identification.