Acute and long‐term outcomes of percutaneous balloon aortic valvuloplasty for the treatment of severe aortic stenosis
Key result
Balloon aortic valvuloplasty in patients with severe aortic stenosis resulted in a 12-month mortality of 22.3% and significantly increased mean aortic valve area from 0.59 to 0.82 cm2 (P<0.05).
Why the study?
Does percutaneous balloon aortic valvuloplasty improve echocardiographic parameters and serve as a bridge to definitive therapy in patients with severe aortic stenosis?
Population
112 patients with severe aortic stenosis (AS)
Design
Cohort
Follow-up
1, 6, and 12 months
Authors
Discussion
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Member takes
Implication
High mortality in this observational cohort advises cautious patient selection; leaves open optimal management strategies pending randomized data.
Key Points
- Evaluate short- and long-term outcomes of balloon aortic valvuloplasty (BAV) in severe aortic stenosis patients.
- Cohort of 112 patients with severe aortic stenosis undergoing 114 BAV procedures between October 2012 and July 2015.
- Clinical and echocardiographic data collected at 1, 6, and 12 months follow-up.
- Procedures took place in two Polish interventional cardiology centers.
- Periprocedural mortality was 2.7%, in-hospital mortality was 8.9%, and 12-month mortality was 22.3%.
- Aortic valve area increased from 0.59 cm² to 0.82 cm², and mean aortic gradient decreased significantly after the procedure (P < 0.05).
- Left ventricular ejection fraction increased significantly in patients with impaired function (median increase of 16% at 1 and 6 months, P < 0.05).
Study Design
Type
Cohort (n=112)
Multicenter
Yes
Structured PICO
Does percutaneous balloon aortic valvuloplasty improve echocardiographic parameters and serve as a bridge to definitive therapy in patients with severe aortic stenosis?
P
Population
112 patients with severe aortic stenosis undergoing balloon aortic valvuloplasty, followed for up to 12 months.
E
Exposure
Percutaneous balloon aortic valvuloplasty (BAV)
O
Outcome
Indications, short- and long-term outcomes including mortality, adverse events, and echocardiographic parametershard clinical
Balloon aortic valvuloplasty is a useful bridging procedure in high-risk patients with severe aortic stenosis, significantly improving echocardiographic parameters and LVEF.
Cite This Study
Daniec et al. (2016) conducted a cohort in severe aortic stenosis (n=112). Balloon aortic valvuloplasty was evaluated on 12-month mortality. Balloon aortic valvuloplasty in patients with severe aortic stenosis resulted in a 12-month mortality of 22.3% and significantly increased mean aortic valve area from 0.59 to 0.82 cm2 (P<0.05).